| RESEARCH: Taking OTC Painkillers During Pregnancy Associated with Male Infertility in Baby | | Print | |
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Taking OTC Painkillers During Pregnancy Associated with Male Infertility in Baby
More than half of pregnant women in the Western world report taking over-the-counter (OTC) painkillers, such as Tylenol, Ibuprofen and Aspirin, but some of these drugs are known hormone disrupters and have been associated with the abnormal development of male sexual organs. In a European study, 491 mothers were asked about their use of OTC painkillers during their pregnancy and pediatricians assessed the male babies for abnormal sexual organ development. It was found that the use of OTC painkillers was dose-dependently associated with congenitally absent or undescended testicles. In particular, use during the second trimester increased the risk. This risk was further increased after the simultaneous use of different types of painkillers."A single [acetaminophen] tablet (500 milligrams) contains more endocrine disruptor potency than the combined exposure to the ten most prevalent of the currenty known environmental endocrine disruptors during the whole pregnancy," said lead researcher Henrik Leffers.
Reference: Human Reproduction. 2011 Jan;26(1):235-44. Epub 2010 Nov 8. Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat. |
